Description

2-(Iodomethyl)-1,1,1,3,3,3-Hexafluoropropane is a specialized fluorinated organic iodide compound, valued for its unique reactivity as a versatile building block in advanced chemical synthesis. Its molecular structure, featuring both a reactive iodomethyl group and a stable hexafluoroisopropyl moiety, makes it a critical intermediate for introducing fluorinated segments into target molecules. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated groups to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, pesticides, and fungicides where fluorination can improve environmental persistence and efficacy.
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, coatings, and liquid crystals with specific thermal, chemical, or surface properties.
• Fluorinated Surfactant & Lubricant Development: Employed in creating fluorocarbon-based surfactants and high-performance lubricants for demanding industrial applications.
• Organic Synthesis Reagent: Utilized in various name reactions (e.g., nucleophilic substitution, radical reactions) as a source of the -CH2I functional group within a fluorinated framework.
• R&D and Process Chemistry: Essential for exploratory chemistry in academic and industrial laboratories for developing new synthetic methodologies and fluorinated compounds.

Basic Information

Product Name	2-(Iodomethyl)-1,1,1,3,3,3-Hexafluoropropane
CAS No.	883449-40-9
Molecular Formula	C4H3F6I
Molecular Weight	307.96 g/mol
Synonyms	1-Iodo-2-(1,1,1,3,3,3-hexafluoropropan-2-yl)ethane; Hexafluoroisopropyl iodomethyl; 2-(Iodomethyl)hexafluoroisopropane; 1,1,1,3,3,3-Hexafluoro-2-(iodomethyl)propane; (Perfluoroisopropyl)methyl iodide; Iodomethyl perfluoroisopropyl ether (common misnomer); HFIP-CH2I; PFP-CH2I
EINECS	Contact for details

Quality Control

Every batch of 2-(Iodomethyl)-1,1,1,3,3,3-Hexafluoropropane is manufactured and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to meet the high standards required for synthetic chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term stability and to minimize decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 95.0%
Purity (by GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.