Description

1-(2-Naphthyl)-3-[(2,3,4,5,6-Pentafluorophenyl)Sulfanyl]-1-Propanone is a specialized fluorinated organic intermediate featuring a unique naphthyl and pentafluorophenylthioether structure. This compound is valued for its role as a key building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its fluorine content and aromatic backbone impart desirable properties. It is primarily sought by research and development teams, as well as process chemists, in the pharmaceutical, agrochemical, and advanced material science industries for creating novel molecules with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the pentafluorophenyl group can enhance lipophilicity and biological activity.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, or organic semiconductors for electronic applications.
• Chemical Biology Probes: Employed in the design of fluorinated probes and tags for studying biological processes and protein interactions due to its distinct spectroscopic signature.
• Catalyst Ligand Development: Investigated as a component in the design of novel ligands for transition metal catalysis, leveraging the electron-withdrawing nature of the pentafluorophenyl group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex fluorinated intermediates.

Basic Information

Product Name	1-(2-Naphthyl)-3-[(2,3,4,5,6-Pentafluorophenyl)Sulfanyl]-1-Propanone
CAS No.	882749-22-6
Molecular Formula	C19H11F5OS
Molecular Weight	382.35 g/mol
Synonyms	3-(Pentafluorophenylthio)-1-(2-naphthyl)-1-propanone; 1-Propanone, 1-(2-naphthalenyl)-3-[(2,3,4,5,6-pentafluorophenyl)thio]-; 1-(Naphthalen-2-yl)-3-(pentafluorophenylthio)propan-1-one; Pentafluorophenyl 2-naphthyl ketone sulfide derivative; 882749-22-6; 3-(Perfluorophenylthio)-1-(2-naphthyl)propan-1-one
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Naphthyl)-3-[(2,3,4,5,6-Pentafluorophenyl)Sulfanyl]-1-Propanone is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.