Description

1-[1,1'-Biphenyl]-4-Yl-3-(3-Fluoro-4-Methylanilino)-1-Propanone is a high-value, specialized organic compound featuring a biphenyl core linked to a propanone chain with a fluoro-methylanilino substituent. This unique molecular architecture makes it a critical advanced intermediate in the synthesis of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a precursor in the development of next-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs, due to its conjugated biphenyl system.
• Ligand and Catalyst Development: The anilino and ketone functional groups make it a useful scaffold for creating novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design of fluorescent probes or affinity tags for studying biological processes and protein interactions.

Basic Information

Product Name	1-[1,1'-Biphenyl]-4-Yl-3-(3-Fluoro-4-Methylanilino)-1-Propanone
CAS No.	882748-59-6
Molecular Formula	C22H20FNO
Molecular Weight	333.40 g/mol
Synonyms	3-[(3-Fluoro-4-methylphenyl)amino]-1-(4-phenylphenyl)propan-1-one; 1-(Biphenyl-4-yl)-3-[(3-fluoro-4-methylphenyl)amino]propan-1-one; 3-(3-Fluoro-4-methylanilino)-1-(4-biphenylyl)-1-propanone; 1-(4-Biphenylyl)-3-[(3-fluoro-4-methylphenyl)amino]-1-propanone; 4'-Benzoyl-3-[(3-fluoro-4-methylphenyl)amino]propiophenone; CAS 882748-59-6
EINECS	Contact for details

Quality Control

Our production of 1-[1,1'-Biphenyl]-4-Yl-3-(3-Fluoro-4-Methylanilino)-1-Propanone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and ISO 9001 standards ensures a reliable supply of this high-purity intermediate for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.