Description

1-(4-Bromophenyl)-3-(2,5-Difluoroanilino)-1-Propanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct bromophenyl and difluoroanilino functional groups. This compound is critical for the synthesis of complex organic molecules, offering researchers and manufacturers a reliable building block for developing new active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring halogenated aromatic structures.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or insecticides where the bromine and fluorine substituents can enhance biological activity and stability.
• Material Science: Used in the development of advanced organic materials, such as ligands for catalysts or monomers for specialty polymers.
• Chemical Synthesis: Employed in academic and industrial laboratories for methodological studies, including cross-coupling reactions and amination protocols.
• Fluorine Chemistry: Acts as a valuable substrate for exploring further fluorination or functionalization reactions due to the presence of the difluoroanilino group.

Basic Information

Product Name	1-(4-Bromophenyl)-3-(2,5-Difluoroanilino)-1-Propanone
CAS No.	882748-47-2
Molecular Formula	C15H12BrF2NO
Molecular Weight	340.17 g/mol
Synonyms	1-Propanone, 1-(4-bromophenyl)-3-[(2,5-difluorophenyl)amino]-; 3-[(2,5-Difluorophenyl)amino]-1-(4-bromophenyl)-1-propanone; 1-(4-Bromophenyl)-3-(2,5-difluorophenylamino)propan-1-one; N-(2,5-Difluorophenyl)-3-(4-bromophenyl)-3-oxopropan-1-amine; 882748-47-2
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)-3-(2,5-Difluoroanilino)-1-Propanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.