Description

n-Isopropyl L-Valinamide is a specialized chiral building block and intermediate of significant interest in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is primarily utilized by research institutions and industrial manufacturers developing active pharmaceutical ingredients (APIs), peptide mimetics, and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Peptidomimetics & Drug Discovery: Used to introduce the valine-derived isopropylamide moiety into peptide backbones to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Serves as a building block for creating chiral active ingredients in crop protection products.
• Asymmetric Catalysis & Ligand Synthesis: Employed in the preparation of chiral ligands and catalysts for stereoselective transformations.
• Chemical Biology Research: Utilized as a probe or precursor in studying enzyme-substrate interactions and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical intermediate for custom synthesis projects requiring high-purity, enantiomerically pure compounds.

Basic Information

Product Name	n-Isopropyl L-Valinamide
CAS No.	882528-81-6
Molecular Formula	C8H18N2O
Molecular Weight	158.24 g/mol
Synonyms	L-Valine, N-(1-methylethyl)-; (S)-2-Amino-3-methyl-N-(propan-2-yl)butanamide; Isopropyl-L-valinamide; Valinamide, N-isopropyl-, L-; N-Isopropyl-L-valine amide; (2S)-2-Amino-3-methyl-N-propan-2-yl-butanamide; L-Valinamide, N-isopropyl-; 882528-81-6
EINECS	Contact for details

Quality Control

Our n-Isopropyl L-Valinamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity verification by HPLC. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is supplied with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.