Description

n-Methyl-3-(trifluoromethyl)benzenesulfonamide is a specialized organosulfur compound featuring a trifluoromethyl-substituted aromatic ring. This high-purity intermediate is valued for its unique combination of a sulfonamide pharmacophore and the lipophilic, electron-withdrawing trifluoromethyl group, which is critical for modulating the biological activity and physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates, particularly for targeted cancer therapies and enzyme inhibitors.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances bioactivity and environmental stability.
• Chemical Biology Probe Development: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Can be utilized in the synthesis of specialty polymers or coatings with specific surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	n-Methyl-3-(trifluoromethyl)benzenesulfonamide
CAS No.	882423-09-8
Molecular Formula	C8H8F3NO2S
Molecular Weight	239.21 g/mol
Synonyms	3-(Trifluoromethyl)-N-methylbenzenesulfonamide; N-Methyl-α,α,α-trifluoro-m-toluenesulfonamide; m-(Trifluoromethyl)-N-methylbenzenesulfonamide; Benzenesulfonamide, N-methyl-3-(trifluoromethyl)-; N-Methyl-3-trifluoromethylbenzenesulfonamide; 3-Trifluoromethyl-N-methylphenylsulfonamide
EINECS	Contact for details

Quality Control

Our n-Methyl-3-(trifluoromethyl)benzenesulfonamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.