Description

Benzenebutanoicacid,B-Amino-2,4,5-Trifluoro-,Methylester,(Br)- CAS NO 881995-69-3 is a high-purity, advanced pharmaceutical intermediate characterized by its specific trifluoro and bromo-substituted aromatic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex active pharmaceutical ingredients (APIs) with targeted properties. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring sophisticated fluorinated molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or oncological pathways.
• Agrochemical Research: Serves as a precursor for developing new-generation fluorinated pesticides and herbicides, where the trifluoro group enhances biological activity and metabolic stability.
• Material Science: Used in the research and development of specialty polymers and advanced organic electronic materials that benefit from halogenated aromatic units.
• Chemical Synthesis: Employed in organic synthesis laboratories for constructing complex molecules, leveraging its amino and ester functional groups for further derivatization.
• Life Science Research: Utilized as a biochemical tool or a labeled compound precursor in proteomics and diagnostic assay development.

Basic Information

Product Name	Benzenebutanoicacid,B-Amino-2,4,5-Trifluoro-,Methylester,(Br)- CAS NO 881995-69-3
CAS No.	881995-69-3
Molecular Formula	C11H11BrF3NO2
Molecular Weight	326.11 g/mol
Synonyms	Methyl 4-Amino-2-(bromomethyl)-3,5,6-trifluorobenzenebutanoate; 4-Amino-2,4,5-trifluoro-γ-bromobenzenebutanoic Acid Methyl Ester; (4-Amino-2,4,5-trifluorophenyl)butanoic Acid Methyl Ester, Bromo Derivative; γ-Bromo-4-amino-2,4,5-trifluorobenzenebutanoic Acid Methyl Ester; 881995-69-3; Bromo-trifluoro-benzenebutanoate Intermediate; Trifluorinated Bromo Phenylalanine Ester Analog
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up processes. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with every shipment. We support compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.