Description

(S)-2-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)-2-Phenylpropanoic Acid is a high-purity, non-natural amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for the production of complex peptides and peptidomimetics, offering precise stereochemical control for research and development. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of novel Active Pharmaceutical Ingredients (APIs) and therapeutic peptides.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS), particularly for introducing sterically hindered or non-proteinogenic residues.
• Drug Discovery & Medicinal Chemistry: Used in the design and construction of peptide-based drug candidates, enzyme inhibitors, and receptor ligands.
• Bioconjugation & Probe Development: Acts as a versatile linker or functional handle for creating bioconjugates, fluorescent probes, and diagnostic agents.
• Academic & Industrial Research: Employed in chemical biology studies and the development of new synthetic methodologies.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and custom organic molecules.

Basic Information

Product Name	(S)-2-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)-2-Phenylpropanoic Acid
CAS No.	881921-11-5
Molecular Formula	C24H21NO4
Molecular Weight	387.43 g/mol
Synonyms	Fmoc-α-methylphenylalanine; Fmoc-α-Me-Phe-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-phenylpropanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-α-methyl-L-phenylalanine; Fmoc-L-α-methylphenylalanine; Fmoc-α-methyl-L-phenylalanine; Nα-Fmoc-α-methyl-L-phenylalanine; (S)-2-(Fmoc-amino)-2-phenylpropanoic acid
EINECS	Contact for details

Quality Control

Our (S)-2-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)-2-Phenylpropanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.