Description

n-(3,5-Difluorophenyl)-4-Fluorobenzamide is a high-purity fluorinated aromatic amide building block essential for advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research and development. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides, leveraging the stability and bioactivity imparted by the fluorine atoms.
• Material Science Precursor: Used in the synthesis of specialty polymers, liquid crystals, and advanced materials where fluorinated aromatic units enhance thermal stability and chemical resistance.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale commercial batches.

Basic Information

Product Name	n-(3,5-Difluorophenyl)-4-Fluorobenzamide, 97%
CAS No.	881767-73-3
Molecular Formula	C13H8F3NO
Molecular Weight	251.21 g/mol
Synonyms	4-Fluoro-N-(3,5-difluorophenyl)benzamide; N-(3,5-Difluorophenyl)-4-fluorobenzamide; 4-Fluorobenzoic acid (3,5-difluoroanilide); 881767-73-3; 4-Fluoro-N-(3,5-difluorophenyl)benzenecarboxamide; Benzamide, N-(3,5-difluorophenyl)-4-fluoro-; 3,5-Difluoroanilino-4-fluorobenzophenone (obsolete)
EINECS	Contact for details

Quality Control

Our n-(3,5-Difluorophenyl)-4-Fluorobenzamide is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming the product meets the 97% minimum purity specification and is free from significant unidentified impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.