Description

Boronic Acid, [2-Fluoro-3-(Trifluoromethoxy)Phenyl]- is a high-value, fluorinated aromatic boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, makes it an essential reagent for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for applications in Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing enhanced metabolic stability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine and trifluoromethoxy groups improve biological activity and environmental persistence.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its electronic properties are advantageous.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global R&D projects.

Basic Information

Item	Detail
Product Name	Boronic Acid, [2-Fluoro-3-(Trifluoromethoxy)Phenyl]-
CAS No.	881402-25-1
Molecular Formula	C7H5BF4O3
Molecular Weight	223.92 g/mol
Synonyms	[2-Fluoro-3-(trifluoromethoxy)phenyl]boronic acid; (2-Fluoro-3-(trifluoromethoxy)phenyl)boronic acid; 2-Fluoro-3-(trifluoromethoxy)benzeneboronic acid; B-[2-Fluoro-3-(trifluoromethoxy)phenyl]boronic acid; 2-Fluoro-α,α,α-trifluoro-m-anisate boronic acid; 881402-25-1; Boronic acid, B-[2-fluoro-3-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our Boronic Acid, [2-Fluoro-3-(Trifluoromethoxy)Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.