Description

2-Fluoro-5-(Trifluoromethoxy)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, including herbicides and fungicides with specific activity profiles.
• Liquid Crystal & OLED Materials: Serves as a building block for synthesizing fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Material Science: Incorporated into specialty polymers and advanced materials to impart specific thermal, chemical, or electronic properties.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for method development and exploring new chemical spaces in medicinal and synthetic chemistry.
• Ligand & Catalyst Design: Acts as a starting material for creating novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2-Fluoro-5-(Trifluoromethoxy)Phenylboronic Acid
CAS No.	881402-22-8
Molecular Formula	C7H5BF4O3
Molecular Weight	223.92 g/mol
Synonyms	[2-Fluoro-5-(trifluoromethoxy)phenyl]boronic acid; (2-Fluoro-5-(trifluoromethoxy)phenyl)boronic acid; 2-Fluoro-5-(trifluoromethoxy)benzeneboronic acid; 881402-22-8; Boronic acid, B-[2-fluoro-5-(trifluoromethoxy)phenyl]-; B-[2-Fluoro-5-(trifluoromethoxy)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Trifluoromethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.