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2-(2,3-Difluoro-4-(Trifluoromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 881402-15-9


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CAS No.:881402-15-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(2,3-Difluoro-4-(Trifluoromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. This compound is valued for its role in facilitating efficient carbon-carbon bond formation, enabling the synthesis of complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing fluorinated aromatic systems.

Application

  • Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly those containing difluorinated and trifluoromethylated aromatic motifs.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the introduction of specific fluorine patterns enhances biological activity and environmental stability.
  • Liquid Crystal & OLED Material Development: Serves as a precursor for creating fluorinated organic semiconductors, charge-transport materials, and emissive layers in display and lighting technologies.
  • Polymer Chemistry: Employed in the synthesis of specialty polymers and functional materials with tailored electronic or surface properties.
  • Chemical Research & Development: An essential tool in academic and industrial labs for exploring new synthetic pathways and creating compound libraries for drug discovery.

Basic Information

Product Name 2-(2,3-Difluoro-4-(Trifluoromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No. 881402-15-9
Molecular Formula C₁₃H₁₄BF₅O₂
Molecular Weight 308.06 g/mol
Synonyms 2,3-Difluoro-4-(trifluoromethyl)phenylboronic acid pinacol ester; (2,3-Difluoro-4-(trifluoromethyl)phenyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-[2,3-difluoro-4-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane; 2-(2,3-Difluoro-4-trifluoromethylphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; Pinacol (2,3-difluoro-4-(trifluoromethyl)phenyl)boronate
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Quality Control

Our 2-(2,3-Difluoro-4-(Trifluoromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere to maintain stability and prevent moisture uptake.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0% (Typical 98-99%)
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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