Description

Otelixizumab CAS NO 881191-44-2 is a chimeric monoclonal antibody designed to target the CD3 antigen on T-cells. This compound is of significant interest for its potential immunomodulatory effects in therapeutic research. It is primarily utilized by pharmaceutical R&D teams and biotechnology companies engaged in the development of novel treatments for autoimmune disorders and for the prevention of organ transplant rejection.

Application

• Primary research and development of novel immunotherapies.
• Investigational studies for the treatment of Type 1 diabetes mellitus.
• Preclinical and clinical research targeting autoimmune diseases.
• Development of therapeutic strategies for islet cell transplantation.
• Mechanistic studies of T-cell mediated immune responses.
• As a critical reference standard in bioanalytical method development.

Basic Information

Product Name	Otelixizumab
CAS No.	881191-44-2
Molecular Formula	C6440H9916N1704O2016S44
Molecular Weight	Approx. 145 kDa
Synonyms	TRX4; ChAglyCD3; Anti-Human CD3, Chimeric (TRX4); Chimeric Anti-CD3 Antibody; TRX-4; GZ-OTLX; Otelixizumab (USAN/INN); Anti-CD3 Monoclonal Antibody TRX4
EINECS	Contact for details

Quality Control

Our Otelixizumab is produced and tested under stringent quality management systems. Each batch is subjected to a comprehensive panel of analytical tests including identity confirmation, purity assessment, and biological activity assays to ensure consistency and reliability for research applications. Certificates of Analysis (COA) detailing purity, endotoxin levels, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Corresponds to reference standard
Purity (SEC-HPLC)	≥ 95% (Monomer)
Protein Content (UV)	≥ 1.0 mg/vial
Endotoxin (LAL)	< 1.0 EU/mg
Biological Activity (Cell-based assay)	Contact for details
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.