Description

4-Bromo-2-(Piperidin-1-Yl)Benzonitrile is a versatile and high-value organic building block featuring a benzonitrile core substituted with bromine and a piperidine moiety. This compound matters as a critical intermediate in modern pharmaceutical and agrochemical research, enabling the synthesis of complex molecules with potential biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Material Science Applications: Can be utilized in the synthesis of organic semiconductors, liquid crystals, or advanced polymers due to its rigid, functionalized aromatic system.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create more complex biaryl structures.

Basic Information

Product Name	4-Bromo-2-(Piperidin-1-Yl)Benzonitrile
CAS No.	881002-28-4
Molecular Formula	C12H13BrN2
Molecular Weight	265.15 g/mol
Synonyms	4-Bromo-2-piperidin-1-ylbenzonitrile; 2-(1-Piperidinyl)-4-bromobenzonitrile; 4-Bromo-2-(1-piperidyl)benzonitrile; 4-Bromo-2-piperidinobenzonitrile; Benzonitrile, 4-bromo-2-(1-piperidinyl)-; 881002-28-4; 4-Bromo-2-piperidino-benzonitrile
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Piperidin-1-Yl)Benzonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically meeting standards for research and development use. We provide comprehensive analytical data including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.