Description

tert-Butyl 4-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex bicyclic structure. This compound is a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) with specific stereochemical and functional properties. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and metabolic disorder research pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Protease Inhibitor Research: Serves as a core scaffold or building block for the development of protease inhibitors, a major class of therapeutic agents.
• Medicinal Chemistry & Drug Discovery: Used in structure-activity relationship (SAR) studies and lead optimization processes to create new molecular libraries.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex nitrogen-containing heterocycles and fused ring systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specific target molecules under cGMP conditions.

Basic Information

Product Name	tert-Butyl 4-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
CAS No.	879686-42-7
Molecular Formula	C12H19NO3
Molecular Weight	225.28 g/mol
Synonyms	tert-Butyl 4-oxo-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate; 2(1H)-Cyclopenta[c]pyrrolecarboxylic acid, 4-oxohexahydro-, 1,1-dimethylethyl ester; 1-Boc-4-oxo-hexahydro-cyclopenta[c]pyrrole; 1-(tert-Butoxycarbonyl)-4-oxohexahydrocyclopenta[c]pyrrole; Boc-4-oxo-hexahydrocyclopenta[c]pyrrole
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with client specifications and relevant industry standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.