Description

n-{3-[(Ethylamino)Carbonyl]-4,5,6,7-Tetrahydro-1-Benzothien-2-Yl}-3-(2-Hydroxy-5-Methylphenyl)-1H-Pyrazole-5-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates, especially those targeting specific enzyme or receptor pathways.
• Drug Discovery Research: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization due to its unique fused ring system.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related APIs.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant scale, requiring consistent high purity and reliable supply.
• Academic Research: Applied in university and institutional research exploring new heterocyclic chemistry and the development of bioactive molecules.

Basic Information

Product Name	n-{3-[(Ethylamino)Carbonyl]-4,5,6,7-Tetrahydro-1-Benzothien-2-Yl}-3-(2-Hydroxy-5-Methylphenyl)-1H-Pyrazole-5-Carboxamide
CAS No.	879444-29-8
Molecular Formula	C22H24N4O3S
Molecular Weight	424.52 g/mol
Synonyms	N-[3-[(Ethylcarbamoyl)-4,5,6,7-tetrahydro-1-benzothien-2-yl]-3-(2-hydroxy-5-methylphenyl)-1H-pyrazole-5-carboxamide; 879444-29-8; UNII-9G2F8W4N5F; Ethyl 2-{5-[(2-hydroxy-5-methylphenyl)carbamoyl]-1H-pyrazol-3-yl}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate derivative; Tetrahydrobenzothienyl pyrazole carboxamide derivative; Advanced Pyrazole-Benzothiophene Intermediate
EINECS	Contact for details

Quality Control

Our n-{3-[(Ethylamino)Carbonyl]-4,5,6,7-Tetrahydro-1-Benzothien-2-Yl}-3-(2-Hydroxy-5-Methylphenyl)-1H-Pyrazole-5-Carboxamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.