Description

1-Fluoro-5-Iodo-2,4-Dimethoxybenzene is a high-purity, multi-functional halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring fluorine and iodine substituents on a dimethoxybenzene scaffold, makes it an exceptionally versatile intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in cross-coupling reactions and as a precursor for specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine and iodine atoms contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive iodine substituent.
• Chemical Biology & Diagnostics: Utilized in the synthesis of probes, tags, and ligands for imaging and diagnostic applications.
• Organic Synthesis & Process R&D: A valuable reagent for method development and scaling novel synthetic routes in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	1-Fluoro-5-Iodo-2,4-Dimethoxybenzene
CAS No.	879288-15-0
Molecular Formula	C8H8FIO2
Molecular Weight	282.05 g/mol
Synonyms	2,4-Dimethoxy-1-fluoro-5-iodobenzene; 5-Iodo-2,4-dimethoxyfluorobenzene; 1-Fluoro-2,4-dimethoxy-5-iodobenzene; Benzene, 1-fluoro-5-iodo-2,4-dimethoxy-; 879288-15-0; FC6H2(OMe)2I (meta-substituted isomer)
EINECS	Contact for details

Quality Control

Our 1-Fluoro-5-Iodo-2,4-Dimethoxybenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and transfer should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.