Description

n-[(3R)-3-Piperidinylmethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is a high-purity, chiral piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for the research and development of novel active pharmaceutical ingredients (APIs), particularly in the fields of neurology and metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring a reliable source of a stereochemically defined intermediate for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates targeting central nervous system (CNS) receptors.
• Agrochemical Research: Used in the development of novel, high-efficacy crop protection agents and pesticides.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a piperidine scaffold with a protected amine functionality.

Basic Information

Product Name	n-[(3R)-3-Piperidinylmethyl]-Carbamic Acid 1,1-Dimethylethyl Ester
CAS No.	879275-33-9
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	tert-Butyl (R)-3-(aminomethyl)piperidine-1-carboxylate; (R)-1-Boc-3-(aminomethyl)piperidine; (R)-3-(Aminomethyl)-1-N-Boc-piperidine; (R)-1-(tert-Butoxycarbonyl)-3-(aminomethyl)piperidine; (R)-N-Boc-3-piperidinemethylamine; (3R)-3-(Aminomethyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; (R)-3-(Aminomethyl)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our n-[(3R)-3-Piperidinylmethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) specifying identity, purity (typically >97%), enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.