Description

(5R)-5-(Chloromethyl)-3-(3-Fluorophenyl)-2-Oxazolidinone is a high-purity chiral building block and pharmaceutical intermediate of significant importance in modern synthetic chemistry. Its value lies in its defined stereochemistry and functional groups, which make it a critical precursor for the development of novel active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new antibiotic and antibacterial agents, particularly within the oxazolidinone class.
• Agrochemical Synthesis: Used as a building block in the production of advanced pesticides and herbicides with specific stereochemical requirements.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in academic and industrial research focused on developing new catalytic methodologies.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of client-specific target molecules.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	(5R)-5-(Chloromethyl)-3-(3-Fluorophenyl)-2-Oxazolidinone
CAS No.	879215-66-4
Molecular Formula	C10H9ClFNO2
Molecular Weight	229.64 g/mol
Synonyms	(5R)-5-(Chloromethyl)-3-(3-fluorophenyl)-1,3-oxazolidin-2-one; (R)-5-(Chloromethyl)-3-(3-fluorophenyl)oxazolidin-2-one; 3-(3-Fluorophenyl)-5R-(chloromethyl)-2-oxazolidinone; (R)-3-(3-Fluorophenyl)-5-(chloromethyl)oxazolidin-2-one; Oxazolidinone derivative 879215-66-4; Chiral oxazolidinone building block; 3-Fluorophenyl oxazolidinone intermediate
EINECS	Contact for details

Quality Control

Our (5R)-5-(Chloromethyl)-3-(3-Fluorophenyl)-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.