Description

tert-Butyl 2-Fluoro-2-Methylpropylcarbamate is a specialized fluorinated carbamate building block of significant interest in advanced organic synthesis. Its core value lies in the strategic incorporation of both a protected amine and a fluorine atom, enabling precise modifications to molecular structure and properties. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental persistence.
• Peptidomimetics & PROTACs: Serves as a versatile precursor for constructing fluorinated amino acid analogs and linkers in complex drug discovery platforms like proteolysis-targeting chimeras.
• Material Science: Potential monomer or modifier in the synthesis of specialty polymers and coatings, where fluorine imparts unique surface properties and chemical resistance.
• Chemical Biology Probes: Employed in the creation of fluorinated probes and tags for studying biological mechanisms and enzyme interactions.

Basic Information

Product Name	tert-Butyl 2-Fluoro-2-Methylpropylcarbamate
CAS No.	879001-62-4
Molecular Formula	C9H18FNO2
Molecular Weight	191.24 g/mol
Synonyms	1,1-Dimethylethyl N-(2-fluoro-2-methylpropyl)carbamate; tert-Butyl N-(2-fluoro-2-methylpropyl)carbamate; 2-Fluoro-2-methylpropylcarbamic acid tert-butyl ester; Boc-2-fluoro-2-methylpropylamine; N-Boc-2-fluoro-2-methylpropylamine; (2-Fluoro-2-methylpropyl)carbamic acid tert-butyl ester; tert-Butyl (2-fluoro-2-methylpropyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Fluoro-2-Methylpropylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.