Description

7-(4-Fluorophenyl)-3,4,5,6-tetrahydro-2H-azepine is a specialized organic building block featuring a fluorinated aromatic ring fused to a seven-membered nitrogen heterocycle. This unique structure makes it a valuable intermediate for the synthesis of novel pharmacologically active compounds and advanced materials. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures. Our supply ensures high purity and batch-to-batch consistency critical for sensitive synthetic applications.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging the bioactivity of the fluorophenyl moiety.
• Ligand & Catalyst Development: Serves as a scaffold for creating novel ligands in asymmetric catalysis and organometallic chemistry.
• Material Science: Building block for advanced polymers and functional materials requiring specific aromatic and heterocyclic components.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Academic & Contract Research: Essential for medicinal chemistry programs and exploratory synthetic research in university and CRO laboratories.

Basic Information

Product Name	7-(4-Fluorophenyl)-3,4,5,6-Tetrahydro-2H-Azepine
CAS No.	878788-23-9
Molecular Formula	C12H14FN
Molecular Weight	191.25 g/mol
Synonyms	7-(4-Fluorophenyl)-2H-azepine, 3,4,5,6-tetrahydro-; 4-Fluorophenylazepane; 1-(4-Fluorophenyl)azepane; 7-(p-Fluorophenyl)hexamethyleneimine; Hexamethyleneimine, 1-(4-fluorophenyl)-; Azepane, 1-(4-fluorophenyl)-; 1-(4-Fluorophenyl)hexahydro-1H-azepine
EINECS	Contact for details

Quality Control

Every batch of 7-(4-Fluorophenyl)-3,4,5,6-tetrahydro-2H-azepine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles by HPLC, GC, and NMR is supplied with each shipment. Our quality commitment supports compliance with cGMP and ISO 9001 standards for reliable sourcing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.