Description

1-(4-Fluorophenyl)-5-Oxo-n-[5-(Propan-2-Yl)-1,3,4-Thiadiazol-2-Yl]Pyrrolidine-3-Carboxamide is a high-value, structurally complex organic compound featuring a pyrrolidine core linked to fluorophenyl and substituted 1,3,4-thiadiazole moieties. This molecular architecture makes it a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing bioactive molecules.

Application

This specialized intermediate is designed for high-end synthetic applications, particularly in drug discovery and development.

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties of lead compounds.
• API (Active Pharmaceutical Ingredient) Development: Employed in the synthetic route development and scale-up of candidate drugs targeting various disease pathways.
• Biochemical Research: May be utilized as a tool compound or probe in biochemical assays to study enzyme inhibition or receptor interaction.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of other complex, fluorinated heterocyclic compounds with specialized applications.

Basic Information

Product Name	1-(4-Fluorophenyl)-5-Oxo-n-[5-(Propan-2-Yl)-1,3,4-Thiadiazol-2-Yl]Pyrrolidine-3-Carboxamide
CAS No.	878731-29-4
Molecular Formula	C₁₆H₁₇FN₄O₂S
Molecular Weight	348.40 g/mol
Synonyms	1-(4-Fluorophenyl)-5-oxo-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]pyrrolidine-3-carboxamide; N-(5-Isopropyl-1,3,4-thiadiazol-2-yl)-1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxamide; 1-(p-Fluorophenyl)-5-oxo-N-(5-isopropyl-1,3,4-thiadiazol-2-yl)pyrrolidine-3-carboxamide; 878731-29-4; CAS 878731-29-4
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.