Description

(2S)-3-(4-{[(2,2-Dimethylpropoxy)Sulfonyl]Oxy}Phenyl)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Propanoic Acid is a sophisticated, high-purity synthetic intermediate designed for advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring precise, protected amino acid derivatives for constructing complex molecules. It is primarily utilized in the pharmaceutical and advanced materials sectors for peptide synthesis, drug discovery, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics for drug development.
• API Synthesis: Used in the research and production of novel Active Pharmaceutical Ingredients (APIs), particularly those requiring Fmoc-protected tyrosine derivatives.
• Bioconjugation: Serves as a reagent for creating antibody-drug conjugates (ADCs) and other targeted therapeutic agents.
• Chemical Biology Research: Employed in the study of protein-protein interactions and enzyme mechanisms as a modified amino acid probe.
• Material Science: Potential use in the synthesis of specialized polymers and advanced functional materials.

Basic Information

Product Name	(2S)-3-(4-{[(2,2-Dimethylpropoxy)Sulfonyl]Oxy}Phenyl)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Propanoic Acid
CAS No.	878408-63-0
Molecular Formula	C29H31NO8S
Molecular Weight	553.63 g/mol
Synonyms	Fmoc-Tyr(SO3Piv)-OH; Fmoc-O-sulfo-L-tyrosine(Piv) ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[(2,2-dimethyl-1-oxopropoxy)sulfonyl]-L-tyrosine; Fmoc-L-tyrosine(O-sulfopivalate); Fmoc-Tyr(SO3Piv)-OH; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-[4-[[(2,2-dimethylpropanoyloxy)sulfonyl]oxy]phenyl]propanoic acid; L-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 4-[(2,2-dimethyl-1-oxopropoxy)sulfonyl] ester
EINECS	Contact for details

Quality Control

Our (2S)-3-(4-{[(2,2-Dimethylpropoxy)Sulfonyl]Oxy}Phenyl)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)Propanoic Acid is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency essential for sensitive pharmaceutical applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of research and production environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere (argon or nitrogen) after each use to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0% (Total area %)
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.