Description

1-(4-Cyanophenyl)-n-Isopropylmethanesulfonamide is a specialized organic intermediate featuring a sulfonamide core with a cyano-substituted aromatic ring. This compound matters for its role as a key building block in the synthesis of advanced pharmaceutical and agrochemical agents, offering a versatile scaffold for further functionalization. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing sulfonamide-based pharmacophores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the sulfonamide and nitrile functional groups.
• Chemical Research & Development: Serves as a versatile building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the creation of compound libraries for high-throughput screening.
• Material Science Precursor: Potential use in the synthesis of advanced polymers or functional materials where the aromatic nitrile group can be further modified.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	1-(4-Cyanophenyl)-n-Isopropylmethanesulfonamide
CAS No.	878218-25-8
Molecular Formula	C11H14N2O2S
Molecular Weight	238.31 g/mol
Synonyms	N-Isopropyl-4-cyanobenzenesulfonamide; 4-Cyano-N-isopropylbenzenesulfonamide; Benzenesulfonamide, 4-cyano-N-(1-methylethyl)-; 1-(4-Cyanophenyl)-N-(propan-2-yl)methanesulfonamide; p-Cyano-N-isopropylbenzenesulfonamide; N-(1-Methylethyl)-4-cyanobenzenesulfonamide; 4-CN-N-iPr-benzenesulfonamide
EINECS	Contact for details

Quality Control

Our 1-(4-Cyanophenyl)-n-Isopropylmethanesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.