Description

2-(Trifluoromethyl)-7,8-Dihydro-6H-Pyrazolo[1,5-A][1,4]Diazepin-4-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure containing a trifluoromethyl group. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Serves as a key building block in the commercial-scale production of active pharmaceutical ingredients for clinical trials and eventual market supply.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for pharmacological studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	2-(Trifluoromethyl)-7,8-Dihydro-6H-Pyrazolo[1,5-A][1,4]Diazepin-4-Ol
CAS No.	877402-85-2
Molecular Formula	C9H8F3N3O
Molecular Weight	231.18 g/mol
Synonyms	2-(Trifluoromethyl)-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-ol; 6H-Pyrazolo[1,5-a][1,4]diazepin-4-ol, 7,8-dihydro-2-(trifluoromethyl)-; 877402-85-2; 2-Trifluoromethyl-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-ol; 4-Hydroxy-2-(trifluoromethyl)-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepine
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)-7,8-Dihydro-6H-Pyrazolo[1,5-A][1,4]Diazepin-4-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All material is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.