Description

4-Bromo-n-Cyclopropyl-2-Fluorobenzamide is a high-purity, advanced pharmaceutical intermediate featuring a unique halogenated benzamide structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its distinct cyclopropyl and halogen motifs into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its halogen and cyclopropyl functional groups.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides and pesticides.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific halogenated benzamide scaffolds.
• Academic Research: Used in university and institutional labs for organic synthesis methodology development and novel heterocycle formation.

Basic Information

Product Name	4-Bromo-n-Cyclopropyl-2-Fluorobenzamide
CAS No.	877383-84-1
Molecular Formula	C10H9BrFNO
Molecular Weight	258.09 g/mol
Synonyms	4-Bromo-N-cyclopropyl-2-fluorobenzamide; 2-Fluoro-4-bromo-N-cyclopropylbenzamide; Benzamide, 4-bromo-N-cyclopropyl-2-fluoro-; 4-Bromo-2-fluoro-N-cyclopropylbenzamide; N-Cyclopropyl-4-bromo-2-fluorobenzamide; 877383-84-1; 4-Bromo-N-cyclopropyl-2-fluorobenzoic acid amide
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-n-Cyclopropyl-2-Fluorobenzamide is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.