Description

4-Bromo-2-Fluoro-n-Isopropylbenzamide is a high-purity, halogenated benzamide derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which facilitates the introduction of both bromine and fluorine substituents into complex target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated aromatic compounds.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Chemical Synthesis: Acts as a versatile building block for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex biaryl systems.
• Life Science Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing tailored intermediates for client projects.

Basic Information

Product Name	4-Bromo-2-Fluoro-n-Isopropylbenzamide
CAS No.	877383-76-1
Molecular Formula	C10H11BrFNO
Molecular Weight	260.10 g/mol
Synonyms	4-Bromo-2-fluoro-N-(propan-2-yl)benzamide; N-Isopropyl-4-bromo-2-fluorobenzamide; 2-Fluoro-4-bromo-N-isopropylbenzamide; Benzamide, 4-bromo-2-fluoro-N-(1-methylethyl)-; 877383-76-1; 4-Bromo-2-fluoro-N-(methylethyl)benzamide
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Fluoro-n-Isopropylbenzamide is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and cGMP intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.