Description

Boc-(Rs)-2-Amino-4-Benzyloxybutanoic Acid is a protected amino acid derivative featuring both a tert-butoxycarbonyl (Boc) protecting group on the amine and a benzyl ether protecting group on the side chain. This compound serves as a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, enabling precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic peptides and small molecule drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a protected amino acid with a functionalized side chain.
• Chemical Biology Research: Employed in the design and synthesis of enzyme inhibitors, receptor ligands, and molecular probes to study biological pathways.
• Process Chemistry: Serves as a starting material or intermediate in the scalable synthesis of active pharmaceutical ingredients (APIs) under GMP conditions.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and asymmetric catalysis.

Basic Information

Product Name	Boc-(Rs)-2-Amino-4-Benzyloxybutanoic Acid
CAS No.	876617-13-9
Molecular Formula	C₁₆H₂₃NO₅
Molecular Weight	309.36 g/mol
Synonyms	(RS)-2-[(tert-Butoxycarbonyl)amino]-4-(benzyloxy)butanoic Acid; N-Boc-4-(Benzyloxy)-DL-homoalanine; 4-(Benzyloxy)-DL-homoalanine N-Boc derivative; Boc-DL-HomoSer(Bzl)-OH; tert-Butyl (RS)-2-amino-4-(benzyloxy)butanoate (acid form); N-(tert-Butoxycarbonyl)-4-(benzyloxy)-DL-homoalanine; DL-2-Amino-4-benzyloxybutyric acid N-Boc derivative
EINECS	Contact for details

Quality Control

Our Boc-(Rs)-2-Amino-4-Benzyloxybutanoic Acid is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided with each shipment. We adhere to relevant industry standards and can support development toward cGMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.