Description

(S)-2-n-Boc-Aminomethylmorpholine CAS NO 875551-59-0 is a high-purity, chiral morpholine derivative featuring a Boc-protected amino group, serving as a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling the stereoselective synthesis of complex molecules, ensuring high enantiomeric purity in final products. This advanced pharmaceutical intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing new active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce high enantioselectivity.
• Peptidomimetics & PROTACs: Used in the construction of peptide backbones and linkers for Proteolysis Targeting Chimeras (PROTACs) due to its morpholine scaffold and protected amine.
• Agrochemical Research: Intermediate in the development of novel, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for specialty polymers and functional materials requiring specific chiral centers.
• Academic & Process R&D: Serves as a standard reagent in university and industrial research laboratories for method development and scale-up studies.

Basic Information

Product Name	(S)-2-n-Boc-Aminomethylmorpholine
CAS No.	875551-59-0
Molecular Formula	C10H20N2O3
Molecular Weight	216.28 g/mol
Synonyms	(S)-tert-Butyl 2-(aminomethyl)morpholine-4-carboxylate; (S)-4-(tert-Butoxycarbonyl)-2-(aminomethyl)morpholine; (S)-N-Boc-2-Aminomethylmorpholine; (S)-2-((tert-Butoxycarbonyl)amino)methyl)morpholine; (S)-2-(Boc-aminomethyl)morpholine; (2S)-2-[[(tert-Butoxycarbonyl)amino]methyl]morpholine; (S)-2-(N-Boc-aminomethyl)morpholine; BOC-(S)-2-Aminomethylmorpholine
EINECS	Contact for details

Quality Control

Our (S)-2-n-Boc-Aminomethylmorpholine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.