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4'-Fluoro-2'-Methoxy-5'-Isopropyl-4-Trifluoromethyl-1,1'-Biphenyl-2-Methanol CAS NO 875548-97-3


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CAS No.:875548-97-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4'-Fluoro-2'-Methoxy-5'-Isopropyl-4-Trifluoromethyl-1,1'-Biphenyl-2-Methanol is a high-value, multi-functional biphenyl derivative featuring strategically positioned fluorine, methoxy, isopropyl, and trifluoromethyl groups. This compound matters as a sophisticated chemical intermediate and building block for advanced synthesis, where its unique substitution pattern enables the development of novel molecules with tailored properties. It is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for creating active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
  • Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
  • Liquid Crystal Materials (LCs): Serves as a precursor for advanced biphenyl-based mesogens used in display technologies, leveraging its rigid core and polarizable substituents.
  • Organic Light-Emitting Diode (OLED) Materials: Acts as a core structure for developing host or emissive layer materials in OLED devices due to its potential for fine-tuning electronic properties.
  • Polymer Chemistry: Can be incorporated as a monomer or cross-linking agent to create specialty polymers with enhanced thermal stability, chemical resistance, or specific optical characteristics.
  • Chemical Research: Employed in academic and industrial laboratories as a versatile scaffold for medicinal chemistry, catalysis, and materials science exploration.

Basic Information

Product Name 4'-Fluoro-2'-Methoxy-5'-Isopropyl-4-Trifluoromethyl-1,1'-Biphenyl-2-Methanol
CAS No. 875548-97-3
Molecular Formula C18H18F4O2
Molecular Weight 342.33 g/mol
Synonyms [4-(4-Fluoro-2-methoxy-5-propan-2-ylphenyl)-3-(trifluoromethyl)phenyl]methanol; 1,1'-Biphenyl-2-methanol, 4'-fluoro-2'-methoxy-5'-(1-methylethyl)-4-(trifluoromethyl)-; 4'-Fluoro-2'-methoxy-5'-isopropyl-4-(trifluoromethyl)biphenyl-2-ylmethanol; 2-Methoxy-4-(1-methylethyl)-4'-(trifluoromethyl)[1,1'-biphenyl]-2-methanol, 5'-fluoro-; 4'-Fluoro-2'-methoxy-5'-isopropyl-4-trifluoromethylbiphenyl-2-methanol; 4'-Fluoro-2'-methoxy-5'-isopropyl-4-trifluoromethyl-1,1'-biphenyl-2-methanol
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Quality Control

Our 4'-Fluoro-2'-Methoxy-5'-Isopropyl-4-Trifluoromethyl-1,1'-Biphenyl-2-Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect against moisture absorption. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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