Description

4-Fluoro-5-Isopropyl-2-Methoxyphenylboronic Acid is a high-purity, multi-substituted phenylboronic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which enables precise structural modifications in target molecules, facilitating the development of novel compounds with specific properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates with complex aryl-ether or biaryl structures.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require the specific fluorinated, isopropyl-substituted phenyl moiety.
• Material Science Research: Building block for organic electronic materials, such as ligands for OLEDs or charge-transport materials, where the boronic acid group enables polymerization or complex formation.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors that leverage boronic acid-diol interactions for detection applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-directed synthesis projects requiring this specific boronic acid derivative.

Basic Information

Product Name	4-Fluoro-5-Isopropyl-2-Methoxyphenylboronic Acid
CAS No.	875446-29-0
Molecular Formula	C10H14BFO3
Molecular Weight	212.03 g/mol
Synonyms	(4-Fluoro-5-isopropyl-2-methoxyphenyl)boronic acid; 2-Methoxy-4-fluoro-5-isopropylbenzeneboronic acid; B-(4-Fluoro-5-isopropyl-2-methoxyphenyl)boronic acid; 4-Fluoro-5-(1-methylethyl)-2-methoxybenzeneboronic acid; Boronic acid, B-[4-fluoro-5-(1-methylethyl)-2-methoxyphenyl]-; 875446-29-0 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 4-Fluoro-5-Isopropyl-2-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.