Description

Secukinumab is a high-purity, fully human monoclonal antibody designed for targeted therapeutic intervention. This product is critical for pharmaceutical research and development, offering a reliable reference standard for analytical and formulation studies. It is primarily utilized by biopharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in immunology and autoimmune disease research.

Application

• Primary use as a reference standard for quality control and analytical method development in biopharmaceutical production.
• Critical raw material for biosimilar development and characterization studies.
• Essential component in pre-clinical research targeting interleukin-17A (IL-17A) pathways.
• Used in assay development for pharmacokinetic (PK) and immunogenicity testing.
• Supplies academic and institutional laboratories for fundamental immunological research.
• Acts as a key material for formulation and stability studies for injectable therapeutics.

Basic Information

Product Name	Secukinumab
CAS No.	875356-43-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	AIN457; Cosentyx; IL-17A Inhibitor AIN457; Anti-IL-17A Monoclonal Antibody; Secukinumab (USAN); Fully Human Anti-Interleukin-17A Monoclonal Antibody; Immunoglobulin G1, anti-(human interleukin 17A) (human monoclonal AIN457 heavy chain), disulfide with human monoclonal AIN457 light chain, dimer
EINECS	Contact for details

Quality Control

Our Secukinumab is manufactured under strict quality systems. Each batch is subjected to a comprehensive suite of analytical tests to ensure identity, purity, potency, and consistency, meeting the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided to support your regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under controlled humidity conditions to maintain stability. For long-term storage, consider aliquoting to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC/CE-SDS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 98.0% (Monomer)
Protein Content (A280)	As per COA
Biological Activity (Cell-based assay)	As per COA
Endotoxin	< 1.0 EU/mg
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.