Description

1H-Indole-7-Carboxylic Acid, 6-Fluoro is a high-purity fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which introduces both the indole scaffold and a carboxylic acid functional group at specific positions, modified by a fluorine atom for enhanced electronic properties and metabolic stability. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in oncology and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the fluorinated indole structure contributes to biological activity.
• Material Science Research: Employed in the synthesis of organic semiconductors and functional dyes due to its electron-rich indole core.
• Biochemical Tool Compound: Serves as a precursor or reference standard in biochemical assays and proteomics research.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, amide bond formation, and other transformations to construct complex heterocyclic systems.

Basic Information

Product Name	1H-Indole-7-Carboxylic Acid, 6-Fluoro
CAS No.	875305-42-3
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	6-Fluoro-1H-indole-7-carboxylic acid; 6-Fluoroindole-7-carboxylic Acid; 7-Carboxy-6-fluoroindole; 6-Fluoro-7-indolecarboxylic acid; 6-Fluoro-1H-indole-7-carboxylic acid; 875305-42-3; 6-Fluoro-7-carboxyindole
EINECS	Contact for details

Quality Control

Our 1H-Indole-7-Carboxylic Acid, 6-Fluoro is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.