Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl Adam-Oh is a specialized Fmoc-protected amino acid derivative, a critical building block in modern solid-phase peptide synthesis (SPPS). Its primary value lies in enabling the controlled, sequential assembly of complex peptides by protecting the amine functionality during coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key protected amino acid building block for the automated synthesis of complex peptide sequences.
• Pharmaceutical Research & Development: Used in the discovery and production of novel peptide-based therapeutics, including hormones, antibiotics, and targeted drug candidates.
• Bioconjugation: Facilitates the site-specific labeling or functionalization of peptides and proteins with other molecules (e.g., fluorophores, drugs, polymers).
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify new bioactive peptide leads.
• Academic & Institutional Research: A fundamental reagent for studying protein structure-function relationships, enzyme substrates, and receptor-ligand interactions.
• Production of Custom Peptides: Used by CROs and CDMOs for the contract manufacturing of research-grade and GMP-grade peptides.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl Adam-Oh
CAS No.	875211-10-2
Molecular Formula	C24H25NO4
Molecular Weight	391.46 g/mol
Synonyms	Fmoc-1-adamantylglycine; Fmoc-Ada-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-adamantylglycine; 1-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-1-adamantaneacetic acid; Fmoc-1-aminoadamantane-1-carboxylic acid; N-Fmoc-1-adamantylglycine; (1-Adamantyl)-N-Fmoc-glycine
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl Adam-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.