Description

Methyl 2-Amino-5-Nitro-4-(Trifluoromethyl)Benzoate is a high-value, multi-functional aromatic building block characterized by its unique trifluoromethyl and nitro-substituted benzoate structure. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecules with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Dye and Pigment Intermediate: Functions as a building block for synthesizing specialized nitro- and amino-substituted dyes and pigments.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Methyl 2-Amino-5-Nitro-4-(Trifluoromethyl)Benzoate
CAS No.	875155-19-4
Molecular Formula	C9H7F3N2O4
Molecular Weight	264.16 g/mol
Synonyms	Methyl 2-Amino-5-Nitro-α,α,α-trifluoro-p-toluate; Benzoic acid, 2-amino-5-nitro-4-(trifluoromethyl)-, methyl ester; 2-Amino-5-nitro-4-(trifluoromethyl)benzoic acid methyl ester; Methyl 2-amino-5-nitro-4-trifluoromethylbenzoate; 4-(Trifluoromethyl)-2-amino-5-nitrobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Amino-5-Nitro-4-(Trifluoromethyl)Benzoate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting identity, purity, and impurity profiles as determined by HPLC, NMR, and other relevant analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.