Description

2-Methoxy-5-(trifluoromethyl)benzamide is a high-purity, specialized benzamide derivative characterized by its methoxy and trifluoromethyl substituents. This compound serves as a critical pharmaceutical intermediate and advanced organic building block for the synthesis of complex molecules. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Building block for developing novel herbicides and fungicides, leveraging the stability imparted by the trifluoromethyl group.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research due to its amide functionality.
• Material Science Research: Serves as a monomer or modifier in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-Methoxy-5-(Trifluoromethyl)Benzamide
CAS No.	874804-06-5
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	2-Methoxy-α,α,α-trifluoro-p-toluamide; 5-(Trifluoromethyl)-2-methoxybenzamide; 2-Methoxy-5-(trifluoromethyl)benzoic acid amide; 2-Methoxy-α,α,α-trifluoro-p-toluylic amide; 874804-06-5; Benzamide, 2-methoxy-5-(trifluoromethyl)-; Amide of 2-methoxy-5-(trifluoromethyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Methoxy-5-(trifluoromethyl)benzamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.