Description

(E)-n-Benzyl-2-Cyano-3-(4-Hydroxyphenyl)-2-Propenamide is a high-purity synthetic intermediate characterized by its distinct α,β-unsaturated cyanoamide structure with a phenolic group. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting enzymes or receptors where the hydroxyphenyl and cyanoamide motifs are critical for bioactivity.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or plant growth regulators, leveraging its structural features for target interaction.
• Material Science: Acts as a monomer or cross-linking agent in the research of specialty polymers, coatings, or adhesives with specific optical or mechanical properties.
• Chemical Biology Probe Development: Employed in creating molecular probes or tags for studying biological processes due to its reactive handles for conjugation.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including reactions like Michael additions or cyclizations, within university and CRO laboratories.

Basic Information

Item	Details
Product Name	(E)-n-Benzyl-2-Cyano-3-(4-Hydroxyphenyl)-2-Propenamide
CAS No.	874655-86-4
Molecular Formula	C17H14N2O2
Molecular Weight	278.31 g/mol
Synonyms	(E)-2-Cyano-N-benzyl-3-(4-hydroxyphenyl)acrylamide; (E)-N-Benzyl-2-cyano-3-(4-hydroxyphenyl)prop-2-enamide; 2-Propenamide, N-benzyl-2-cyano-3-(4-hydroxyphenyl)-, (2E)-; Benzyl 2-cyano-3-(4-hydroxyphenyl)propenoate derivative; α-Cyano-N-benzyl-4-hydroxycinnamamide
EINECS	Contact for details

Quality Control

Our (E)-n-Benzyl-2-Cyano-3-(4-Hydroxyphenyl)-2-Propenamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets exacting R&D and process chemistry standards. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.