Description

n-Cbz-o-Bzl-L-Glu-S-Bzl-L-Cys-Gly[13C2,15N]-Obzl is a stable isotope-labeled peptide derivative, specifically designed for advanced research and analytical applications. This compound is critical for use as an internal standard in mass spectrometry, enabling highly accurate quantification and metabolic pathway tracing in proteomics and pharmacokinetic studies. It is an essential tool for pharmaceutical R&D, academic research, and biotechnology laboratories focused on peptide chemistry, biomarker discovery, and drug development.

Application

• Mass Spectrometry Internal Standard: Used for precise quantification in LC-MS/MS and GC-MS analyses to ensure data accuracy and reproducibility.
• Proteomics Research: Facilitates the study of protein expression, post-translational modifications, and protein-protein interactions.
• Metabolic Pathway Tracing: Employed in stable isotope labeling studies to track the incorporation and fate of amino acids in biological systems.
• Pharmaceutical Development: Serves as a key reference material in the pharmacokinetic and pharmacodynamic profiling of peptide-based drug candidates.
• Biomarker Discovery & Validation: Provides a stable isotopic signature for the reliable identification and validation of peptide biomarkers in complex biological matrices.
• Peptide Synthesis & Characterization: Acts as a building block or analytical standard in the synthesis and quality control of novel peptides.

Basic Information

Product Name	n-Cbz-o-Bzl-L-Glu-S-Bzl-L-Cys-Gly[13C2,15N]-Obzl
CAS No.	874462-72-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-Carbobenzoxy-O-benzyl-L-glutamyl-S-benzyl-L-cysteinyl-Glycine[13C2,15N]-benzyl ester; Cbz-Glu(OBzl)-Cys(Bzl)-Gly[13C2,15N]-OBzl; Isotope-labeled Cbz-Glu(OBzl)-Cys(Bzl)-Gly-OBzl; [13C2,15N]-Glycine labeled tripeptide derivative; Benzyl N-[(benzyloxy)carbonyl]-L-γ-glutamyl-S-benzyl-L-cysteinyl-[13C2,15N]glycinate; Stable isotope-labeled protected tripeptide; 874462-72-3
EINECS	Contact for details

Quality Control

Our n-Cbz-o-Bzl-L-Glu-S-Bzl-L-Cys-Gly[13C2,15N]-Obzl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for isotopic enrichment verification, and NMR for structural confirmation, to ensure it meets the exacting standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and all relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment	≥ 98 atom % 13C; ≥ 98 atom % 15N
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.