Description

2-Fluoro-4-Ethoxycarbonylphenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, active ingredient synthesis, and specialty polymer development.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific aryl-fluorine motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid coupling partner for creating biaryl and heterobiaryl structures.
• Ligand and Catalyst Development: A precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Advanced Material Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying biological processes.

Basic Information

Product Name	2-Fluoro-4-Ethoxycarbonylphenylboronic Acid
CAS No.	874459-62-8
Molecular Formula	C9H10BFO4
Molecular Weight	211.99 g/mol
Synonyms	(2-Fluoro-4-(ethoxycarbonyl)phenyl)boronic Acid; 4-Carbethoxy-2-fluorophenylboronic Acid; 2-Fluoro-4-(ethoxycarbonyl)benzeneboronic Acid; Ethyl 2-Fluoro-4-boronobenzoate; 2-Fluoro-4-(ethoxycarbonyl)benzeneboronic Acid; Boronic acid, B-[2-fluoro-4-(ethoxycarbonyl)phenyl]-; 874459-62-8
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Ethoxycarbonylphenylboronic Acid undergoes rigorous analytical testing to ensure it meets the high standards required for research and production. Our quality assurance protocols include advanced chromatographic and spectroscopic methods to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.