Description

Propanamide, n-(4-Ethynylphenyl)- is a specialized organic building block featuring both an amide linkage and a terminal alkyne functional group. This unique bifunctional structure makes it a valuable intermediate for advanced synthesis, particularly in the development of pharmaceuticals and functional materials. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring alkyne-amide pharmacophores or linkers.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, resins, and advanced organic frameworks.
• Click Chemistry: The terminal alkyne group makes it an ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, a cornerstone of bioconjugation and polymer chemistry.
• Chemical Research: A versatile reagent for academic and industrial R&D in organic synthesis and medicinal chemistry.
• Ligand and Catalyst Development: Used to create novel ligands for metal catalysts or as a precursor for catalytic systems.

Basic Information

Product Name	Propanamide, n-(4-Ethynylphenyl)-
CAS No.	874379-93-8
Molecular Formula	C11H9NO
Molecular Weight	171.20 g/mol
Synonyms	N-(4-Ethynylphenyl)propanamide; 4-Ethynyl-N-propionylaniline; 1-Propanamide, N-(4-ethynylphenyl)-; p-Ethynylphenylpropionamide; Propionyl-(4-ethynyl-aniline); (4-Ethynylphenyl)propionamide; N-(4-Ethynylphenyl)propionamide
EINECS	Contact for details

Quality Control

Our Propanamide, n-(4-Ethynylphenyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.