Description

cis-2-Boc-Amino-Cyclopentanecarbonitrile is a high-purity, protected amino acid derivative featuring a cyclopentane backbone. This compound is a critical chiral building block in the synthesis of complex pharmaceutical intermediates and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including protease inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors and other active pharmaceutical ingredients (APIs).
• Peptidomimetics Research: Used in the design and construction of constrained peptide analogs to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Serves as a versatile precursor for introducing the cyclopentyl moiety with defined stereochemistry into target molecules.
• Medicinal Chemistry: Employed in lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Chemical Biology Probes: Useful for creating labeled or modified compounds to study biological pathways and enzyme functions.

Basic Information

Item	Detail
Product Name	cis-2-Boc-Amino-Cyclopentanecarbonitrile
CAS No.	874293-97-7
Molecular Formula	C12H20N2O2
Molecular Weight	224.30 g/mol
Synonyms	(1S,2R)-2-[(tert-Butoxycarbonyl)amino]cyclopentanecarbonitrile; (1S,2R)-2-[(tert-Butoxycarbonyl)amino]cyclopentane-1-carbonitrile; cis-2-[(tert-Butoxycarbonyl)amino]cyclopentanecarbonitrile; cis-2-(Boc-amino)cyclopentanecarbonitrile; Boc-cis-2-ACPCN; (1S,2R)-2-(Boc-amino)cyclopentanecarbonitrile
EINECS	Contact for details

Quality Control

Our cis-2-Boc-Amino-Cyclopentanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) with full chromatographic data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.