Description

3-(Benzyloxycarbonylamino)-5-Fluorophenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a protected amine group with a boronic acid moiety, making it a versatile intermediate for constructing complex molecules via cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a crucial boronic acid coupling partner for forming carbon-carbon bonds in complex molecule assembly.
• Peptidomimetic & PROTAC Development: Used in the construction of peptide-like molecules and Proteolysis Targeting Chimeras (PROTACs) due to its protected amino group.
• Agrochemical Synthesis: Employed in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules to study biological processes and pathways.

Basic Information

Product Name	3-(Benzyloxycarbonylamino)-5-Fluorophenylboronic Acid
CAS No.	874290-61-6
Molecular Formula	C14H13BFNO4
Molecular Weight	289.07 g/mol
Synonyms	5-Fluoro-3-[[(phenylmethoxy)carbonyl]amino]benzeneboronic Acid; N-Cbz-3-Amino-5-fluorophenylboronic Acid; 3-(N-Cbz-amino)-5-fluorophenylboronic Acid; (Z)-3-Amino-5-fluorophenylboronic Acid; 3-[(Benzyloxycarbonyl)amino]-5-fluorobenzeneboronic Acid; CAS 874290-61-6; Benzyl N-(3-borono-5-fluorophenyl)carbamate
EINECS	Contact for details

Quality Control

Our 3-(Benzyloxycarbonylamino)-5-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.