Description

5-(Cbz-Amino)-2-Fluorophenylboronic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected amino group and a boronic acid functionality. This compound is critical for the synthesis of complex molecules, particularly in the development of novel therapeutics and agrochemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in medicinal chemistry and cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting specific biological pathways.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid reagent for forming carbon-carbon bonds in the construction of complex biaryl structures.
• Medicinal Chemistry Research: Used in drug discovery programs for the design and optimization of new drug candidates with improved efficacy and safety profiles.
• Protease Inhibitor Development: The Cbz-protected amino acid derivative structure makes it valuable for creating peptide mimetics and enzyme inhibitors.
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Potential use in the creation of organic electronic materials and advanced polymers through its reactive functional groups.

Basic Information

Item	Details
Product Name	5-(Cbz-Amino)-2-Fluorophenylboronic Acid
CAS No.	874290-58-1
Molecular Formula	C14H13BFNO4
Molecular Weight	289.07 g/mol
Synonyms	5-[(Benzyloxycarbonyl)amino]-2-fluorobenzeneboronic acid; N-Cbz-5-Amino-2-fluorophenylboronic Acid; 2-Fluoro-5-[(phenylmethoxy)carbonyl]aminobenzeneboronic acid; 5-(N-Carbobenzyloxyamino)-2-fluorophenylboronic acid; 5-Amino-2-fluorophenylboronic acid N-carboxybenzyl derivative; B-[5-[[(Benzyloxy)carbonyl]amino]-2-fluorophenyl]boronic acid; Boc Equivalent for Amino-Fluoro Phenyl Boronic Acid (Cbz-protected)
EINECS	Contact for details

Quality Control

Our 5-(Cbz-Amino)-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.