Description

2-Fluoro-5-(Methoxycarbamoyl)Benzeneboronic Acid is a high-value, multi-functional boronic acid derivative used as a critical building block in advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing fluorinated aromatic systems.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to create complex biaryl structures, a cornerstone of modern medicinal chemistry.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific fluorinated motifs.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, polymers, and liquid crystals.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors due to its boronic acid functionality which can interact with diols.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Fluoro-5-(Methoxycarbamoyl)Benzeneboronic Acid
CAS No.	874289-58-4
Molecular Formula	C9H11BFNO4
Molecular Weight	226.99 g/mol
Synonyms	[2-Fluoro-5-(methoxycarbamoyl)phenyl]boronic acid; (2-Fluoro-5-methoxyaminocarbonylphenyl)boronic acid; 5-Carbamoyl-2-fluorobenzeneboronic acid methyl derivative; 2-Fluoro-5-(N-methoxycarbamoyl)benzeneboronic acid; Boronic acid, B-[2-fluoro-5-[(methoxyamino)carbonyl]phenyl]-; 874289-58-4 (CAS Index Name)
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(Methoxycarbamoyl)Benzeneboronic Acid is produced and tested under a strict quality management system to ensure consistency and reliability for your critical synthesis workflows. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.