Description

2-Fluoro-5-(Hydrazinecarbonyl)Benzeneboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, combining a boronic acid group, a hydrazinecarbonyl linker, and a fluorine substituent, makes it a versatile reagent for constructing complex molecular architectures. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for applications in Suzuki-Miyaura cross-coupling and as a precursor for heterocycle synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or heterocyclic motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific fluorine-containing scaffolds.
• Suzuki-Miyaura Cross-Coupling: Acts as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, essential for creating complex organic molecules.
• Material Science Research: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology & Proteomics: Serves as a reagent for bioconjugation and the development of chemical probes due to its reactive hydrazide and boronic acid groups.
• Ligand Synthesis: Precursor for creating specialized ligands used in catalysis and metal complexation.

Basic Information

Product Name	2-Fluoro-5-(Hydrazinecarbonyl)Benzeneboronic Acid
CAS No.	874289-56-2
Molecular Formula	C7H8BFN2O3
Molecular Weight	197.96 g/mol
Synonyms	2-Fluoro-5-(hydrazinecarbonyl)phenylboronic acid; (2-Fluoro-5-(hydrazinecarbonyl)phenyl)boronic acid; 5-Borono-2-fluorobenzoic acid hydrazide; Benzeneboronic acid, 2-fluoro-5-(hydrazinecarbonyl)-; 2-Fluoro-5-hydrazinylcarbonylbenzeneboronic acid; 874289-56-2; 2-Fluoro-5-carboxyhydrazidophenylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Hydrazinecarbonyl)Benzeneboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.