Description

2-Fluoro-5-(Propylcarbamoyl)Benzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group with a fluoro-substituted aromatic ring and a propylcarbamoyl side chain, enabling precise cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients through Suzuki-Miyaura coupling.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of novel organic electronic materials and functional polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and protein interactions.
• Ligand Development for Catalysis: Utilized to create sophisticated ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-5-(Propylcarbamoyl)Benzeneboronic Acid
CAS No.	874289-48-2
Molecular Formula	C10H13BFNO3
Molecular Weight	225.03 g/mol
Synonyms	[2-Fluoro-5-(propylaminocarbonyl)phenyl]boronic acid; 2-Fluoro-5-(propylcarbamoyl)phenylboronic acid; 5-Carbamoyl-2-fluorobenzeneboronic acid, N-propyl-; B-[2-Fluoro-5-[(propylamino)carbonyl]phenyl]boronic acid; 874289-48-2; AKOS BRN-0768; FT-0658081; 2-Fluoro-5-propylcarbamoylbenzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Propylcarbamoyl)Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications in GMP and research-grade environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.