Description

5-(Dimethylcarbamoyl)-2-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its dual functionality, serving as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions while also offering a protected amide group for further derivatization. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex biaryl and heterobiaryl scaffolds central to active ingredient development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated biaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as an organoboron reagent to form carbon-carbon bonds with aryl or vinyl halides, enabling the construction of complex molecular architectures.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides, fungicides, and insecticides that require specific fluorinated structures.
• Material Science Research: Serves as a monomer or building block for creating advanced organic materials, such as polymers or ligands for catalysts.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and inhibitors for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	5-(Dimethylcarbamoyl)-2-Fluorobenzeneboronic Acid
CAS No.	874289-46-0
Molecular Formula	C9H11BFNO3
Molecular Weight	210.99 g/mol
Synonyms	2-Fluoro-5-(dimethylcarbamoyl)benzeneboronic Acid; (2-Fluoro-5-(N,N-dimethylcarbamoyl)phenyl)boronic Acid; 5-(Dimethylaminocarbonyl)-2-fluorobenzeneboronic Acid; 2-Fluoro-5-(dimethylcarbamoyl)phenylboronic Acid; 874289-46-0; B-[2-Fluoro-5-[(dimethylamino)carbonyl]phenyl]boronic Acid
EINECS	Contact for details

Quality Control

Our 5-(Dimethylcarbamoyl)-2-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.