Description

5-(Cyclohexylcarbamoyl)-2-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative designed for advanced chemical synthesis. This compound serves as a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient and selective formation of biaryl bonds, a fundamental transformation in constructing complex molecular architectures.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific fluorinated aromatic structures.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes, enzyme inhibitors, and activity-based protein profiling reagents.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-(Cyclohexylcarbamoyl)-2-Fluorobenzeneboronic Acid
CAS No.	874289-44-8
Molecular Formula	C13H17BFNO3
Molecular Weight	265.09 g/mol
Synonyms	2-Fluoro-5-[(cyclohexylamino)carbonyl]benzeneboronic Acid; [2-Fluoro-5-(cyclohexylcarbamoyl)phenyl]boronic Acid; 5-(Cyclohexylcarbamoyl)-2-fluorophenylboronic Acid; B-[2-Fluoro-5-[(cyclohexylamino)carbonyl]phenyl]boronic Acid; 874289-44-8; 2-Fluoro-5-(cyclohexylcarbamoyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 5-(Cyclohexylcarbamoyl)-2-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (as C13H17BFNO3)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.