Description

2-Fluoro-5-(Pyrrolidine-1-Carbonyl)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling it to act as a versatile coupling partner in cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who are developing novel active ingredients, particularly for creating complex biaryl and heterobiaryl structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Serves as a crucial boron-containing partner for constructing carbon-carbon bonds between aromatic rings.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific fluorinated biaryl motifs.
• Material Science: Employed in the creation of advanced organic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and enzyme inhibitors.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Detail
Product Name	2-Fluoro-5-(Pyrrolidine-1-Carbonyl)Phenylboronic Acid
CAS No.	874289-42-6
Molecular Formula	C11H13BFNO3
Molecular Weight	237.04 g/mol
Synonyms	(2-Fluoro-5-(pyrrolidine-1-carbonyl)phenyl)boronic acid; 2-Fluoro-5-(1-pyrrolidinecarbonyl)benzeneboronic acid; 5-Borono-2-fluoro-N-pyrrolidylbenzamide; 874289-42-6; Boronic acid, B-[2-fluoro-5-(1-pyrrolidinylcarbonyl)phenyl]-; [2-Fluoro-5-(pyrrolidine-1-carbonyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Pyrrolidine-1-Carbonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications in regulated environments, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.