Description

5-Carbamoyl-2-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, serving as a versatile intermediate for constructing complex molecules via cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science: Serves as a monomer or building block for creating specialized polymers and organic electronic materials.
• Chemical Biology: Employed in the development of probes and inhibitors for studying biological pathways and enzyme functions.
• Catalyst Ligand Synthesis: Utilized to prepare novel ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and fragments for drug discovery programs.

Basic Information

Product Name	5-Carbamoyl-2-Fluorobenzeneboronic Acid
CAS No.	874289-39-1
Molecular Formula	C7H7BFNO3
Molecular Weight	182.95 g/mol
Synonyms	2-Fluoro-5-carbamoylbenzeneboronic Acid; (2-Fluoro-5-carbamoylphenyl)boronic Acid; 5-Carbamoyl-2-fluorophenylboronic Acid; 2-Fluoro-5-aminocarbonylbenzeneboronic Acid; Boronic acid, B-(2-fluoro-5-carbamoylphenyl)-; 874289-39-1; AKOS025311324
EINECS	Contact for details

Quality Control

Every batch of 5-Carbamoyl-2-Fluorobenzeneboronic Acid is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.